CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 20 enrolled
Drug / intervention
Fluciclovine F18 +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04750473
NCT04750473Phase 1Completed

Phase 1 Feasibility Trial: Improved Staging of Lobular Breast Cancer With Novel Amino Acid Metabolic and Tumor Neovasculature Receptor Imaging

Emory University·interventional·Posted Feb 11, 2021·Updated Jan 17, 2025

In Brief

A Phase 1 clinical trial evaluating Computed Tomography, Fluciclovine F18, and 2 other interventions for Anatomic Stage IV Breast Cancer AJCC v8 and 3 related conditions. Completed, enrolled 20 participants across 1 site.

Detailed Summary

This phase I trial studies how well fluciclovine positron emission tomography (PET)/computed tomography (CT) and PSMA PET/CT work in helping doctors understand and classify invasive lobular breast cancer in patients with invasive lobular breast cancer that is suspicious for or has spread to other places in the body (metastasized). Fluciclovine and PSMA are radiotracers used in PET/CT imaging scans that emit radiation. The PET/CT scan than picks up the radiation being released to create a picture from within the body. Information learned from this study may help researchers learn how to better identify metastatic disease in invasive lobular breast cancer patients which will impact appropriate staging.

Study Details

Timeline

Phase 1CompletedFinished
202120222023202420252026
First PostedFeb 11, 2021
Enrollment StartJul 16, 2021
Primary CompletionMar 21, 2023
Study CompletionMar 21, 2024
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 5.4 years ago

Interventions

Computed Tomographyprocedure

Undergo PET/CT scan

Fluciclovine F18drug

Given IV

Gallium Ga 68 Gozetotidedrug

Given IV

Positron Emission Tomographyprocedure

Undergo PET/CT scan