CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 108 enrolled
Drug / intervention
Moxifloxacin (Topical)drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04750655
NCT04750655Phase 4Completed

Antibiotic Resistance In Eye Surgeries (ARIES)

University of California, San Francisco·interventional·Posted Feb 11, 2021·Updated Mar 28, 2025

In Brief

A Phase 4 clinical trial evaluating Moxifloxacin (Topical) for Antibiotic Resistance and 2 related conditions. Completed, enrolled 108 participants across 1 site.

Detailed Summary

In this study, the investigators seek to determine the effect of antibiotic use post-surgery on antimicrobial resistance. The investigators will be studying adults (aged 18 or older) who will undergo eye surgery at University of California, San Francisco (UCSF). We seek to gain a better understanding of how antibiotic use during the perioperative period influences local and systemic antibiotic resistance at the individual level.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
202120222023202420252026
First PostedFeb 11, 2021
Enrollment StartMar 1, 2021
Primary CompletionAug 10, 2023
Study CompletionAug 31, 2023
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 5.4 years ago

Interventions

Moxifloxacin (Topical)drug

We are using moxifloxacin as indicated and as intended for use as an antibiotic during surgery. Frequency of postoperative antibiotics dependent on group randomization.