At a glance
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Lasix for the Prevention of De Novo Postpartum Hypertension: A Randomized Controlled Trial (LAPP Trial)
In Brief
A Phase 3 clinical trial evaluating Furosemide and Placebo for Postpartum Pregnancy-Induced Hypertension and 3 related conditions. Completed, enrolled 82 participants across 1 site.
Detailed Summary
Primary objective: To evaluate whether oral furosemide can help prevent de novo postpartum hypertension (new-onset high blood pressure after delivery) by reducing blood pressure after delivery in high-risk women. Secondary objectives: To evaluate whether oral furosemide administered to high-risk women after delivery can reduce the frequency of postpartum hypertensive episodes, the need for antihypertensive therapy, the risk of postpartum preeclampsia, and the incidence of severe maternal morbidity.
Study Details
Timeline
Interventions
Furosemide 20 mg pill taken daily for 5 days
Identical-appearing placebo pill taken daily for 5 days