CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 3 enrolled
Drug / intervention
Bevacizumab +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04753216
NCT04753216Phase 2Completed

A Phase II Trial of Irinotecan Liposome and Bevacizumab in Women With Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Northwestern University·interventional·Posted Feb 15, 2021·Updated Jan 19, 2023

In Brief

A Phase 2 clinical trial evaluating Bevacizumab and Irinotecan Sucrosofate for Platinum-Resistant Fallopian Tube Carcinoma and 8 related conditions. Completed, enrolled 3 participants across 1 site.

Detailed Summary

This phase II trial investigates the effect of irinotecan liposome and bevacizumab in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that shows less response to platinum therapy (platinum resistant), has come back (recurrent), or does not respond to treatment (refractory). Irinotecan liposome may help block the formation of growths that may become cancer. Bevacizumab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. Giving irinotecan liposome and bevacizumab may kill more cancer cells.

Study Details

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedFeb 15, 2021
Enrollment StartMar 16, 2021
Primary CompletionAug 31, 2021
Study CompletionOct 25, 2021
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 5.4 years ago

Interventions

Bevacizumabbiological

Given IV

Irinotecan Sucrosofatedrug

Given IV