CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 726 enrolled
Drug / intervention
BNT162b2 +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04754594
NCT04754594Phase 3Completed

A PHASE 2/3, PLACEBO-CONTROLLED, RANDOMIZED, OBSERVER-BLIND STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF A SARS-COV-2 RNA VACCINE CANDIDATE (BNT162b2) AGAINST COVID-19 IN HEALTHY PREGNANT WOMEN 18 YEARS OF AGE AND OLDER

BioNTech SE·interventional·Posted Feb 15, 2021·Updated Dec 6, 2024

In Brief

A Phase 3 clinical trial evaluating BNT162b2 and Placebo for SARS-CoV-2 Infection and 2 related conditions. Completed, enrolled 726 participants across 90 sites in 5 countries.

Detailed Summary

Results will be submitted, however please note that data are not yet available for all serology outcome measures. This will be a Phase 2/3, randomized, placebo-controlled, observer-blind study evaluating the safety, tolerability, and immunogenicity of 30 µg of BNT162b2 or placebo administered in 2 doses, 21 days apart, in approximately 350 healthy pregnant women 18 years of age or older vaccinated at 24 to 34 weeks' gestation. Participants will be randomized 1:1 to receive BNT162b2 or placebo (saline).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBrazil, South Africa, Spain, United Kingdom, United States
CollaboratorsPfizer

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedFeb 15, 2021
Enrollment StartFeb 16, 2021
Primary CompletionJul 15, 2022
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 5.4 years ago

Interventions

BNT162b2biological

Intramuscular Injection

Placeboother

Intramuscular Injection