CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 8 enrolled
Drug / intervention
NI-0501 +1 moredrug
Likely dose
NI-0501 1 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04765553
NCT04765553Phase 1Completed

A Randomized, Double-blinded, Placebo-controlled, Single Center, Phase I Study to Evaluate Pharmacokinetics, Pharmacodynamics and Safety of Emapalumab After a Single Intravenous Dose in Japanese Healthy Volunteers.

Swedish Orphan Biovitrum·interventional·Posted Feb 21, 2021·Updated Nov 30, 2023

In Brief

A Phase 1 clinical trial evaluating NI-0501 and Saline for Rare Diseases. Completed, enrolled 8 participants across 1 site.

Detailed Summary

This is a randomized, placebo controlled and double-blinded study to evaluate the pharmacokinetics (PK), pharmacodynamics (PD) and safety of a single dose (1 mg/kg) of emapalumab in adult healthy Japanese subjects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRare Diseases
CountriesJapan
Collaborators--

Timeline

Phase 1CompletedFinished
202120222023202420252026
First PostedFeb 21, 2021
Enrollment StartJan 14, 2021
Primary CompletionJun 25, 2021
Study CompletionJul 25, 2021
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 5.4 years ago

Interventions

NI-0501drug

emapalumab single i.v infusion (1 mg/kg)

Salinedrug

Saline single i.v infusion