CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 128 enrolled
Drug / intervention
Efruxifermin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04767529
NCT04767529Phase 2Completed

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Non-Cirrhotic Subjects With Nonalcoholic Steatohepatitis (NASH)

Akero Therapeutics, Inc·interventional·Posted Feb 23, 2021·Updated Jun 18, 2025

In Brief

A Phase 2 clinical trial evaluating Efruxifermin and Placebo for NASH - Nonalcoholic Steatohepatitis. Completed, enrolled 128 participants across 55 sites in 2 countries.

Detailed Summary

This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in non-cirrhotic subjects with biopsy-proven F2 - F3 NASH.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPuerto Rico, United States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedFeb 23, 2021
Enrollment StartFeb 16, 2021
Primary CompletionMay 2, 2024
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 5.4 years ago

Interventions

Efruxifermindrug

subcutaneous injection

Placebodrug

subcutaneous injection