CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 75 enrolled
Drug / intervention
Standard Percutaneous Nephrolithotomy (sPCNL) +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04767919
NCT04767919N/ACompleted

Randomized Controlled Trial to Compare the Operative Outcomes and Complications of Mini-percutaneous Nephrolithotomy (Mini-PCNL) Versus Standard PCNL

University of California, San Diego·interventional·Posted Feb 23, 2021·Updated Mar 27, 2025

In Brief

A clinical study evaluating Standard Percutaneous Nephrolithotomy (sPCNL) and Minimally Invasive Percutaneous Nephrolithotomy (MIP) for Kidney Stone. Completed, enrolled 75 participants across 6 sites in 2 countries.

Detailed Summary

The decision to use standard percutaneous nephrolithotomy (PCNL) versus mini-percutaneous nephrolithotomy (MIP) has been a subject of much debate in the urological community. The investigators propose a randomized controlled trial to compare the operative outcomes and complications of mini-percutaneous nephrolithotomy (mini-PCNL) versus standard PCNL for renal stones. The results of this study will help guide the decision making regarding these two procedures in the US population and provide further insight into the utility and safety of these procedures. A cost analysis will be performed, and it is hypothesized that the reusable components of the Storz MIP set will result in lower costs of the mini-PCNL procedure compared to standard PCNL.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKidney Stone
CountriesCanada, United States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedFeb 23, 2021
Enrollment StartJan 1, 2021
Primary CompletionJun 7, 2024
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 5.4 years ago

Interventions

Standard Percutaneous Nephrolithotomy (sPCNL)procedure

Endoscopic stone procedure using a laser placed in the kidney through an 30 Fr access sheath following balloon dilation.

Minimally Invasive Percutaneous Nephrolithotomy (MIP)procedure

Endoscopic stone procedure using a laser placed in the kidney through an 18 Fr access sheath following either balloon dilation or dilation using a single step metal dilator.