CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 934 enrolled
Drug / intervention
Provision of multiple self-tests +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04772469
NCT04772469N/ACompleted

Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in Men

University of California, San Francisco·interventional·Posted Feb 26, 2021·Updated Apr 29, 2025

In Brief

A clinical study evaluating Provision of multiple self-tests, Small monetary incentives, and 1 other intervention for Human Immunodeficiency Virus and 7 related conditions. Completed, enrolled 934 participants across 1 site.

Detailed Summary

This is a randomized controlled trial to test a combination behavioral and biomedical interventions to improve the HIV prevention and care cascades in a population of mobile men in a high priority setting (fishermen in Kenya). The intervention strategy is to recruit and train highly socially-connected men to distribute HIV self-tests and provide linkage support to men in their close social networks. The study will determine whether this social network-based approach along with small financial incentives in the form of transport vouchers can increase men's self-testing, linkage to and uptake of ART and PrEP after self-testing, virologic suppression at 6 months (for those initiating ART) and PrEP adherence (for those initiating PrEP) at 6 months. The study includes a longitudinal qualitative and mixed methods (quantitative and qualitative assessments) to identify the pathways of intervention action, and understand how the social network-based approach with support for linkage affects testing and ART and PrEP uptake and retention in men.

Study Details

Timeline

N/ACompletedFinished
20222023202420252026
First PostedFeb 26, 2021
Enrollment StartMar 22, 2021
Primary CompletionApr 26, 2023
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 5.4 years ago

Interventions

Provision of multiple self-testsbehavioral

Participants will be given multiple Oraquick Advance HIV-1/2 test kits for testing themselves more frequently and for men in their social networks.

Small monetary incentivesother

Use of small incentive voucher (\~$5) to encourage linkage to confirmatory testing.

Use of SMS/text reminders to motivate adherence to ART or PrEPbehavioral

Messages will be motivational, will not include any identifying information and will include generic texts such as "maintain your good health", to cater for status-neutral language that can work for both HIV positive individuals taking ARVs, as well as HIV-negative individuals on PrEP who may need adherence support.