CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 654 enrolled
Drug / intervention
Roflumilast Cream 0.15% +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04773587
NCT04773587Phase 3Completed

A Phase 3, 4-Week, Parallel Group, Double Blind, Vehicle-Controlled Study of the Safety and Efficacy of ARQ-151 Cream 0.15% Administered QD in Subjects With Atopic Dermatitis

Arcutis Biotherapeutics, Inc.·interventional·Posted Feb 26, 2021·Updated Oct 9, 2024

In Brief

A Phase 3 clinical trial evaluating Roflumilast Cream 0.15% and Vehicle Cream for Atopic Dermatitis Eczema. Completed, enrolled 654 participants across 49 sites in 2 countries.

Detailed Summary

This is a parallel group, double blind, vehicle-controlled study to assess the safety and efficacy of roflumilast (ARQ-151) cream vs vehicle applied once daily (qd) for 4 weeks by participants with atopic dermatitis (eczema).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedFeb 26, 2021
Enrollment StartJan 27, 2021
Primary CompletionAug 30, 2022
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 5.4 years ago

Interventions

Roflumilast Cream 0.15%drug

Roflumilast Cream 0.15% - Active

Vehicle Creamdrug

Cream - Vehicle