CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 683 enrolled
Drug / intervention
Roflumilast Cream +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04773600
NCT04773600Phase 3Completed

A Phase 3, 4-Week, Parallel Group, Double Blind, Vehicle-Controlled Study of the Safety and Efficacy of ARQ-151 Cream 0.15% Administered QD in Subjects With Atopic Dermatitis

Arcutis Biotherapeutics, Inc.·interventional·Posted Feb 26, 2021·Updated Oct 4, 2024

In Brief

A Phase 3 clinical trial evaluating Roflumilast Cream and Vehicle cream for Atopic Dermatitis Eczema. Completed, enrolled 683 participants across 53 sites in 2 countries.

Detailed Summary

This study will assess the safety and efficacy of ARQ-151 cream vs vehicle applied once a day for 4 weeks by subjects with atopic dermatitis (eczema). This is a parallel group, double blind, vehicle-controlled study in which ARQ-151 0.15% cream or vehicle is applied once daily (qd) for 4 weeks by participants with atopic dermatitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedFeb 26, 2021
Enrollment StartFeb 24, 2021
Primary CompletionSep 29, 2022
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 5.4 years ago

Interventions

Roflumilast Creamdrug

Roflumilast cream 0.15% for topical application

Vehicle creamdrug

Vehicle cream for topical application