CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 48 enrolled
Drug / intervention
EndoZip Systemdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04773795
NCT04773795N/ACompleted
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Evaluation of EndoZip System in Obese Patients Who Failed to Reduce Weight With Non-surgical Weight-loss Methods

Nitinotes Surgical Ltd.·interventional·Posted Feb 26, 2021·Updated Aug 13, 2025

In Brief

A clinical study evaluating EndoZip System for Obesity. Completed, enrolled 48 participants across 1 site.

Detailed Summary

A multicenter, prospective, single-arm, open-label, controlled clinical trial aimed to evaluate the safety and effectiveness of the EndoZip system procedure, coupled with lifestyle modifications, for weight reduction in obese patients with BMI of 30-40 kg/m2.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity
CountriesSpain
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedFeb 26, 2021
Enrollment StartJun 30, 2021
Primary CompletionFeb 10, 2023
Study CompletionJul 3, 2023
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 5.4 years ago

Interventions

EndoZip Systemdevice

The Nitinotes EndoZip system is designed to allow for the creation of multiple internal gastric segmentation (4-8) in the stomach by using an endoscopic approach. The system allows the forming of wall-to-wall longitudinal attachments of the anterior and posterior stomach walls, creating multiple strictures within. Creation of this segmentation may significantly reduce gastric volume, may affect gastric motility and consequently, reduce weight.