CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 65 enrolled
Drug / intervention
Celecoxib +2 moredrug
Likely dose
Celecoxib 200mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04790812
NCT04790812Phase 4Completed
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Single Dose Oral Celecoxib (With or Without Acetaminophen) for Acute Post-operative Pain Following Impacted Third Molar Surgery.

The University of Texas Health Science Center, Houston·interventional·Posted Mar 10, 2021·Updated Mar 27, 2024

In Brief

A Phase 4 clinical trial evaluating Celecoxib, Acetaminophen, and 1 other intervention for Pain, Postoperative. Completed, enrolled 65 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) \[celecoxib plus placebo\] to an NSAID combination \[celecoxib plus acetaminophen\] administered preemptively to patients prior to impacted third molar surgery. .

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20222023202420252026
First PostedMar 10, 2021
Enrollment StartApr 22, 2021
Primary CompletionMar 1, 2023
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 5.3 years ago

Interventions

Celecoxibdrug

Single, preemptive oral dose 200mg of celecoxib. A cyclooxygenase-2 (COX-2) selective inhibitor for pain management. A COX-2 selective nonsteroidal anti-inflammatory drug (NSAID).

Acetaminophendrug

Single, preemptive oral dose 1000mg of acetaminophen. An over-the-counter medication for pain management.

Placebodrug

A capsule with no active ingredients designed to mimic the appearance of the acetaminophen capsule to ensure blinding of patients and care providers.