At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
NCT04798573N/AActiveUpdate OverdueUpdated 11mo ago · Completion was 18mo agoPhenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain: A Multicenter Prospective Study
In Brief
An observational study for Chronic Pain and Surgery. Active but no longer recruiting, targeting 10,000 participants across 1 site.
Signals
Detailed Summary
The investigators will approach elective cardiac and thoracic surgery patients in the preoperative consultation clinic. Consenting individuals will be administered, before surgery validated pain, psychological and sleep questionnaires. These questionnaires will be repeated at 3, 6 and 12 months postoperatively (PO) to follow up the progression of early PO pain and the transition to chronicity. Participants will define clinically relevant pain by calculating a chronic pain index (CPI). In addition, the investigators will follow the development of acute postsurgical and chronic pain from before surgery up to a year after, extract DNA from blood and contrast the genetic variations of participants with clinically significant chronic pain, to identify variations associated with the development of chronic post-surgical pain.