At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Role of Mirtazapine in Ameliorating Sleep Disordered Breathing
In Brief
A Phase 2 clinical trial evaluating Mirtazapine and Placebo for Spinal Cord Injuries and Sleep Disordered Breathing. Completed, enrolled 18 participants.
Detailed Summary
The purpose of this study is to look at the effect of using Mirtazapine to target a specific pathway in the body, that relies on a natural chemical the body produces called 'serotonin', in patients with spinal cord injury (SCI) and non-injured persons during sleep. During this part of the study participants will be asked to take Mirtazapine (15mg per day) and a placebo in a random fashion, each for a one week period (drug period) of time followed by one week without drugs (washout period). The drugs will not be taken all at the same time, but each will be taken separately for one weeks followed by a night study to look at the effect the Mirtazapine/placebo pill has on the way the body responds during sleep.
Study Details
Timeline
Interventions
15 mg dose before bed-time
One placebo pill before bed-time