CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,004 enrolled
Drug / intervention
CHALO! 2.0 +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04814654
NCT04814654N/ACompleted
CompareCT.gov

CHALO! 2.0: A Mobile Technology Based Intervention to Accelerate HIV Testing and Linkage to Preventive Treatment.

Albert Einstein College of Medicine·interventional·Posted Mar 24, 2021·Updated Jan 20, 2026

In Brief

A clinical study evaluating CHALO! 2.0, Attention-matched control (AMC), and 1 other intervention for Hiv. Completed, enrolled 1,004 participants across 1 site.

Detailed Summary

While HIV prevalence among Men Seeking Men (MSM) in India is 10-15 times higher than in the general population (4.3% vs 0.3%), current interventions for Indian MSM have limited reach. In order to reduce the burden of HIV in MSM, innovative, far-reaching prevention and treatment strategies are needed. Guided by the increase access to internet-based social and mobile technologies (SMT) (e.g., SMS, WhatsApp, dating apps) globally and in India, this is a 3-arm parallel, pragmatic randomized controlled trial of community-developed, theory based behavioral intervention (CHALO! 2.0) delivered via WhatsApp (secure SMS application) compared to an Attention-Matched Control, or a Digital Coupon for free HIV testing only control conditions. The primary outcomes are HIV-testing at 6 months (3 months after the end of the intervention) and linkage-to-preventive care (counseling or pre-exposure prophylaxis) at 12 months. The secondary outcomes are the frequency of HIV-testing by 18 months.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHiv
CountriesIndia
CollaboratorsThe Humsafar Trust, National Institute of Mental Health (NIMH), Hunter College of City University of New York, Fenway Community Health

Timeline

N/ACompletedFinished
20222023202420252026
First PostedMar 24, 2021
Enrollment StartApr 22, 2022
Primary CompletionJun 27, 2024
Study CompletionDec 30, 2024
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 5.3 years ago

Interventions

CHALO! 2.0behavioral

The components of the intervention are: Contents of digital-media (sent twice/week for 12 weeks) on the following topics: HIV testing, prevention, treatment, linkage-to-care; Personalized digital coupon for free testing; Webpage listing testing/ care sites; access to online outreach workers.

Attention-matched control (AMC)behavioral

The components of the intervention are: Contents of digital-media (sent twice/week for 12 weeks) only related to general health information; Personalized digital coupon for free testing; Webpage listing testing/ care sites; access to online outreach workers.

Digital coupon only (DCO)behavioral

The components of the intervention are: Digital coupon for free HIV testing; Webpage listing testing/ care sites; access to online outreach workers.