CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 150 enrolled
Drug / intervention
High intensity inspiratory and expiratory muscle trainingother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04826575
NCT04826575N/ACompleted

High Intensity Respiratory Muscle Training as a Pre-habilitation in Lung Surgery

St. Anne's University Hospital Brno, Czech Republic·interventional·Posted Apr 1, 2021·Updated May 15, 2025

In Brief

A clinical study evaluating High intensity inspiratory and expiratory muscle training for Lung Cancer and Post-Op Complication. Completed, enrolled 150 participants across 3 sites.

Detailed Summary

We hypothesize that high intensity respiratory muscle training will improve ventilatory efficiency (VE/VCO2 slope) and will be associated with decreased PPC, decreased mortality and better quality of life in lung resection candidates. Accordingly, the aim of this study will be to compare rest and exercise ventilation and gas exchange parameters as well as postoperative complications, quality of life and mortality in patients who undergo high intensity respiratory muscle training compared to patients who receive the usual standard of care.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCzechia

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 1, 2021
Enrollment StartMar 25, 2021
Primary CompletionDec 31, 2024
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 5.3 years ago

Interventions

High intensity inspiratory and expiratory muscle trainingother

Inspiratory Muscle Training will be performed using the Threshold inspiratory muscle trainer device (Threshold IMT®, Philips Respironics, Inc., Murrysville, PA, USA). Expiratory muscle training (EMT) will be performed using the Threshold positive expiratory pressure device (Threshold PEP®, Philips Respironics, Inc., Murrysville, PA, USA) or Expiratory Muscle Strength Trainer EMST 150TM (Aspire Products), depending on the initial MEP. Patients will train 2 times a day, 7 days per week, for 2 weeks.