CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 13 enrolled
Drug / intervention
RMC-035 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04829916
NCT04829916Phase 1Completed

A Phase 1b, Randomised, Double-Blind, Parallel Treatment Group Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RMC-035 in Subjects Undergoing Non-Emergent On-Pump Coronary Artery Bypass Graft and/or Valve Surgery

Guard Therapeutics AB·interventional·Posted Apr 2, 2021·Updated Apr 23, 2024

In Brief

A Phase 1 clinical trial evaluating RMC-035 and Placebo for Acute Kidney Injury (AKI). Completed, enrolled 13 participants across 1 site.

Detailed Summary

The purpose of the clinical study is to assess safety, tolerability and pharmacokinetics of RMC-035 for the prevention and treatment of acute kidney injury (AKI) in patients undergoing cardiac surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany
Collaborators--

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedApr 2, 2021
Enrollment StartMar 16, 2021
Primary CompletionJul 15, 2021
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 5.3 years ago

Interventions

RMC-035drug

Multiple dosing during 48 hours following cardiac surgery

Placebodrug

Multiple dosing during 48 hours following cardiac surgery