At a glance
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Depression-Reduction by Accelerated Personalized NeuroModulation and Its Effects on Sleep
In Brief
An observational study evaluating intermittent theta burst stimulation (iTBS) or sham stimulation for Major Depressive Episode and 2 related conditions. Completed, enrolled 102 participants across 1 site.
Detailed Summary
Advances in repetitive transcranial magnetic stimulation (rTMS) protocols with intermittent theta-burst stimulation (iTBS) have significantly decreased the duration for one single session and thereby enabled accelerated treatment plans with multiple sessions per day, potentially reducing the total treatment duration. This randomized, placebo-controlled study investigates the effects of accelerated iTBS treatment with connectivity-informed neuronavigation on symptom severity, sleep, interoception, and cognitive control in patients with major depressive disorder and with or without comorbid borderline personality disorder using magnetic resonance imaging (MRI).
Study Details
Timeline
Interventions
30 sessions of iTBS over 2 weeks (3 sessions per day, 5 days per week)