CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 195 enrolled
Drug / intervention
[18F]CTT1057drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04838626
NCT04838626Phase 3Completed

Phase II/III Study for Evaluation of the Diagnostic Performance of [18F]CTT1057 PET Imaging for the Detection of PSMA Positive Tumors Using Histopathology as a Standard of Truth

Novartis Pharmaceuticals·interventional·Posted Apr 9, 2021·Updated Oct 7, 2025

In Brief

A Phase 3 clinical trial evaluating [18F]CTT1057 for Prostatic Neoplasms and Prostate Cancer. Completed, enrolled 195 participants across 16 sites in 5 countries.

Detailed Summary

The purpose of this study was to evaluate the diagnostic performance of \[18F\]CTT1057 as a PET imaging agent for detection and localization of PSMA positive tumors using histopathology as Standard of Truth (SoT). Tissue specimens from both the primary tumor and pelvic lymph nodes dissected during surgery from patients with newly-diagnosed high-risk prostate cancer (PCa) were used for the histopathology assessments.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance, Italy, Spain, Switzerland, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedApr 9, 2021
Enrollment StartSep 7, 2021
Primary CompletionNov 24, 2023
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 5.2 years ago

Interventions

[18F]CTT1057drug

PET/CT imaging with \[18F\]CTT1057