CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 86 enrolled
Drug / intervention
Demand Informed Moderator Analysisbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04842500
NCT04842500N/ACompleted

Translational Research to Inform Interventions for Severe Challenging Behavior for Individuals With Intellectual and Developmental Disabilities

Vanderbilt University·interventional·Posted Apr 13, 2021·Updated Feb 6, 2025

In Brief

A clinical study evaluating Demand Informed Moderator Analysis for Behavior and Behavior Mechanisms. Completed, enrolled 86 participants across 5 sites.

Detailed Summary

This project is meant to identify relations between the reinforcement histories of 80 adults with intellectual and developmental disabilities (IDD) and the prevalence of extinction bursts. Extinction bursts, or temporary increases in rates and intensities of behavior during extinction, often preclude the inclusion of extinction in intervention packages meant to suppress severe challenging behavior, despite the fact that extinction is often necessary to generate therapeutic outcomes. Study results will provide insight into how researchers can enhance interventions for the severe challenging behavior of individuals with IDD while mitigating the undesirable collateral effects (i.e., extinction bursts) of therapeutic action (i.e., extinction). Expanded access to study results will be made available to those who inquire after all data have been obtained and analyzed.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 13, 2021
Enrollment StartAug 1, 2021
Primary CompletionMay 24, 2023
Study CompletionMay 14, 2024
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 5.2 years ago

Interventions

Demand Informed Moderator Analysisbehavioral

This analysis is designed to determine the degree to which relative price, and the timing of extinction, interact to increase or abate responding during extinction (thereby highlighting mechanisms of control).