CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Guided bone regeneration with a PTFE membrane +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04843488
NCT04843488N/ACompleted
CompareCT.gov

Effectiveness of Different Membrane Applications (Perforated Polytetrafluroethylene (PTFE) vs. Perforated PTFE+ Collagen Membrane) in Vertical Ridge Augmentation - Randomized Clinical Trial

Urban Regeneration Institute·interventional·Posted Apr 13, 2021·Updated Dec 4, 2024

In Brief

A clinical study evaluating Guided bone regeneration with a PTFE membrane and Guided bone regeneration with a PTFE+collagen membrane for Bone Regeneration and 2 related conditions. Completed, enrolled 30 participants across 1 site.

Detailed Summary

This randomized clinical trial (RCT) study investigates if there is any difference in absolute vertical bone gain between perforated dense-polytetrafluroethylene (d-PTFE) mesh vs perforated d-PTFE mesh covered with a native collagen membrane. The primary endpoint is absolute vertical bone gain. The secondary endpoints are regeneration rate, complications rate, and pseudoperiosteum formation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBone Regeneration, Dental Implants, Polytetrafluoroethylene
CountriesHungary
CollaboratorsSzeged University

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 13, 2021
Enrollment StartApr 15, 2021
Primary CompletionNov 12, 2022
Study CompletionMay 2, 2023
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 5.2 years ago

Interventions

Guided bone regeneration with a PTFE membraneprocedure

Xenograft bovine spongious bone substitute mixed with autogenous intraorally harvested particulated bone is used and spatially contained with a PTFE membrane secured with Ti pins and screws.

Guided bone regeneration with a PTFE+collagen membraneprocedure

Xenograft bovine spongious bone substitute mixed with autogenous intraorally harvested particulated bone is used and spatially contained with a PTFE membrane secured with Ti pins and screws and covered with a Collagen membrane subsequently.