CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 2,020 enrolled / 2,020 target
Drug / intervention
IVUS +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04854070
NCT04854070N/ACompletedOn Track (36.1/mo)Completion was 10mo ago

Intravascular Ultrasound Guidance for Complex High-risk Indicated Procedures

ECRI bv·interventional·Posted Apr 22, 2021·Updated Jun 23, 2026

In Brief

A clinical study evaluating IVUS and Angio for Complex Coronary Lesions. Completed, enrolled 2,020 participants across 37 sites in 7 countries.

Detailed Summary

The IVUS CHIP trial is a post-marketing strategy study in which patients with complex coronary lesions, undergoing percutaneous coronary intervention (PCI), are treated either with intravascular ultrasound (IVUS) guided PCI or angiographic guided PCI . The IVUS-guided PCI approach is indicated to reduce the frequency of target-lesion failure (cardiac death, target-vessel myocardial infarction, and clinically indicated target-lesion revascularization) in patients with complex coronary lesions undergoing PCI. The objective of this study is to assess the superiority of an IVUS-guided approach versus an angio-guided approach in patients with complex coronary lesions undergoing PCI.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, France, Germany, Italy, Netherlands, Spain, United Kingdom

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 22, 2021
Enrollment StartNov 2, 2021
Primary CompletionAug 25, 2025
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 5.2 years ago

Arms & Interventions

IVUS-guided PCIexperimental

Method is already used in standard care, but in this trial compared to another method also already used in standard care

Device: IVUS
Angio-guided PCIactive_comparator

Method is standard care

Device: Angio

Interventions

IVUSdevice

IVUS-guided approach in patients with complex coronary lesions undergoing PCI

Angiodevice

Angio-guided approach in patients with complex coronary lesions undergoing PCI