CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 972 enrolled
Drug / intervention
CoSTED Interventionbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04854616
NCT04854616N/ACompleted

Cessation of Smoking Trial in the Emergency Department

Norfolk and Norwich University Hospitals NHS Foundation Trust·interventional·Posted Apr 22, 2021·Updated Apr 30, 2026

In Brief

A clinical study evaluating CoSTED Intervention for Smoking Cessation and 3 related conditions. Completed, enrolled 972 participants across 1 site.

Detailed Summary

The Cessation of Smoking Trial in the Emergency Department (CoSTED) is an National Institute for Health Research (NIHR) Health Technology Assessment (HTA) funded randomised controlled trial (RCT). The research question is "in people attending the Emergency Department who smoke, does a brief intervention (including the provision of an electronic cigarette (e-cigarette) and referral to stop smoking services) increase smoking cessation in comparison with usual care and is it cost effective?" The trial includes an internal pilot, health economic evaluation and process evaluation. The primary outcome is smoking cessation, self-reported as continuous smoking abstinence, biochemically validated by carbon monoxide monitoring with cut off of ≥8ppm. The sample size is 972 (486 in intervention and control) across 6 sites.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 22, 2021
Enrollment StartJan 4, 2022
Primary CompletionMar 31, 2023
Study CompletionSep 30, 2023
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 5.2 years ago

Interventions

CoSTED Interventionbehavioral

Brief smoking cessation advice, the provision of an e-cigarette starter kit and training in its use, and referral to stop smoking services.