CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 80 enrolled
Drug / intervention
Marine microalgae Tetraselmis chuii with high Superoxide Dismutase (SOD) activity +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04864314
NCT04864314N/ACompleted

A Double-blind Randomized Placebo-controlled Clinical Study to Verify the Efficacy of TetraSOD® in the Improvement of Semen Quality in Patients With Idiopathic Infertility

Fitoplancton Marino, S.L.·interventional·Posted Apr 28, 2021·Updated Mar 27, 2026

In Brief

A clinical study evaluating Marine microalgae Tetraselmis chuii with high Superoxide Dismutase (SOD) activity and Sham for Infertility, Male. Completed, enrolled 80 participants across 2 sites.

Detailed Summary

TetraSOD® is a unique marine phytoplankton (Tetraselmis chuii) SOD-rich ingredient that is grown under patent-protected technology exclusively designed by the company Fitoplancton Marino, S.L. (Spain). In a previous pilot trial, the ability of TetraSOD® to improve semen characteristics in idiopathic infertile men after three months of treatment was assessed, revealing significant improvements in almost all of the analyzed parameters. In the present clinical trial, such positive effects will be tested again in a higher number of patients, and additional parameters will be included in order to gain insights into the sperm physiological changes that underpin the improvement in semen quality

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSpain

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 28, 2021
Enrollment StartMay 12, 2021
Primary CompletionJun 30, 2024
Study CompletionOct 31, 2024
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 5.2 years ago

Interventions

Marine microalgae Tetraselmis chuii with high Superoxide Dismutase (SOD) activitydietary

Participants in the Experimental group will receive a daily dose of 250 mg of TetraSOD® in a capsule during 90 days. After treatment, the group will stop consumption of TetraSOD® and a wash-out period of three months will start

Shamdietary

Participants in the Control group will receive a daily dose of placebo in a capsule during 90 days. After treatment, the group will stop consumption of placebo and a wash-out period of three months will start