At a glance
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Role of Neuralized1 and RGS14 Genes With ASD Patients
In Brief
An observational study evaluating Neurl1 gene expression and RGS14 gene expression for Autism Spectrum Disorder and 2 related conditions. Completed, enrolled 60 participants.
Detailed Summary
Autism is a broad spectrum neurodevelopmental disease. Some individuals with ADS by high cognitive functions are diagnosed with High Functioning Autism (HFA). In some studies, it has been shown that NEURL1 gene increases learning and memory and RGS14 gene is suppressed them. We aimed to evaluate the differences between the expression levels of these genes between ASD, HFA and healthy controls and the role of these genes in the pathogenesis of ASD. Patients with 20 ASD and 20 HFA, and 20 healthy controls compatible with patient ages were included in this study. Expression of NEURL-1 and RGS14 genes was evaluated by quantitative Real Time PCR (qRT-PCR).
Study Details
Timeline
Interventions
This observational case control study. The gene expression was examined.
This observational case control study. The gene expression was examined.