CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Transcranial Direct Current Stimulation (tDCS) +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04866771
NCT04866771N/ACompleted

Remotely Supervised Transcranial Direct Current Stimulation for Slowing Disease Progression in Amyotrophic Lateral Sclerosis (ALS)

University of Illinois at Chicago·interventional·Posted Apr 30, 2021·Updated Aug 7, 2025

In Brief

A clinical study evaluating Transcranial Direct Current Stimulation (tDCS) and Sham tDCS + anodal tDCS for Amyotrophic Lateral Sclerosis (ALS). Completed, enrolled 14 participants across 1 site.

Detailed Summary

Most ALS care is centered on patient support and symptom management, making rehabilitation an integral aspect for slowing disease progression, prolonging life span, and increasing quality of life. Brain stimulation has been increasingly explored as a promising neuromodulatory tool to prime motor function in several neurological disorders. We propose a novel mechanism using remotely supervised brain stimulation to preserve motor function in individuals with ALS. This project will also aim to explore the effectiveness of brain stimulation on upper and lower motor neuron mechanisms in individuals with ALS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 30, 2021
Enrollment StartAug 27, 2021
Primary CompletionJul 1, 2024
Study CompletionJan 1, 2025
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 5.2 years ago

Interventions

Transcranial Direct Current Stimulation (tDCS)other

Noninvasive brain stimulation

Sham tDCS + anodal tDCSother

Fake noninvasive brain stimulation or anodal noninvasive brain stimulation