CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 151 enrolled
Drug / intervention
RZL-012 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04867434
NCT04867434Phase 2Completed

A Double Blind, Randomized, Three Arm, Placebo-Controlled Phase 2b Study to Evaluate the Efficacy and Safety of RZL-012 in Subjects Seeking for Submental Fat Reduction

Raziel Therapeutics Ltd.·interventional·Posted Apr 30, 2021·Updated Sep 28, 2023

In Brief

A Phase 2 clinical trial evaluating RZL-012 and Placebo for Submental Fat. Completed, enrolled 151 participants across 1 site.

Detailed Summary

A total of 135 eligible male or female subjects will be randomized according to a predetermined randomization scheme (1:1:1 ratio) to receive a single multi-injection treatment of high dose RZL-012, low dose RZL-012, or placebo on Day 0. They will be monitored for safety and efficacy over 84 days.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSubmental Fat
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedApr 30, 2021
Enrollment StartJun 15, 2021
Primary CompletionApr 20, 2022
Study CompletionMay 31, 2022
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 5.2 years ago

Interventions

RZL-012drug

small synthetic molecule for submental fat reduction

Placebodrug

Placebo