CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 4 enrolled
Drug / intervention
DFV890drug
Likely dose
DFV890 100 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04868968
NCT04868968Phase 2Completed

An Open-label, Single Arm Phase II Study of DFV890 to Assess the Safety, Tolerability and Efficacy in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS)

Novartis Pharmaceuticals·interventional·Posted May 3, 2021·Updated Oct 9, 2024

In Brief

A Phase 2 clinical trial evaluating DFV890 for Familial Cold Autoinflammatory Syndrome. Completed, enrolled 4 participants across 3 sites in 3 countries.

Detailed Summary

The purpose of this phase II study was to assess the safety, tolerability and efficacy of DFV890 in participants with FCAS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance, Germany, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedMay 3, 2021
Enrollment StartSep 20, 2021
Primary CompletionDec 13, 2022
Study CompletionMay 5, 2023
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 5.2 years ago

Interventions

DFV890drug

100 mg of DFV890 film coated tablets twice daily (b.i.d.). for 3 days starting in the morning of Day 1 and 100 mg of DFV890 in the morning on the fourth day.