CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 141 enrolled
Drug / intervention
Doing What Matters in Times of Stress: An Illustrated Guidebehavioral
Likely dose
Self-guided WHO stress management guide (Doing What Matters in Times of Stress: An Illustrated Guide) practiced a few minutes dailyAI-extracted
Key inclusion· 2
  • At least mild distress measured by K6 score ≥6
  • Regular access to internet or telephone
Key exclusion· 1
  • Active suicidality: PHQ-9 item 9 score ≥2 ('more than half the days')

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04870099
NCT04870099N/ACompleted

Leveraging Computational Social Sciences and Natural Language Processing to Optimize Engagement and Response to Low-intensity CBT for Depression and Anxiety

Indiana University·interventional·Posted May 3, 2021·Updated Aug 3, 2025

In Brief

A clinical study evaluating Doing What Matters in Times of Stress: An Illustrated Guide for Bibliotherapy. Completed, enrolled 141 participants across 1 site.

Detailed Summary

Common mental disorders (CMDs) like depression and anxiety account for a large proportion of disability worldwide. Access to effective treatments like cognitive-behavioral therapy (CBT) is limited and has not reduced the public health burden of psychopathology. For patients with mild-moderate CMDs, lower-intensity treatments like guided self-help CBT (GSH-CBT) are effective and more scalable (e.g., via the internet). The advent of social media has opened avenues for dissemination of GSH-CBTs and allows for passive sensing of mood, thinking, behavior, and social networks. We propose to leverage a social media platform used by over a fifth of the United States (Twitter) as a recruitment tool to virtually screen over 150 individuals, recruit N=60 to a 5-week course of GSH-CBT, and extract social media data from individuals engaged in GSH-CBT. Sociodemographic and social media data will be used to predict engagement, outcomes, and processes in GSH-CBT.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBibliotherapy
CountriesUnited States

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedMay 3, 2021
Enrollment StartOct 17, 2020
Primary CompletionFeb 21, 2022
Study CompletionMay 21, 2022
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 5.2 years ago

Interventions

Doing What Matters in Times of Stress: An Illustrated Guidebehavioral

From the WHO's website: Doing What Matters in Times of Stress: An Illustrated Guide is a stress management guide for coping with adversity. The guide aims to equip people with practical skills to help cope with stress. A few minutes each day are enough to practice the self-help techniques. The guide can be used alone or with the accompanying audio exercises. Informed by evidence and extensive field testing, the guide is for anyone who experiences stress, wherever they live and whatever their circumstances.