At a glance
ClinicalIndex Comparison Record- ✓Right-sided colon cancer from caecum to proximal third of transverse colon
- ✓Tumor stage T2-T4a, any N, or T any N+ with no distant metastasis
- ✓ASA grade I-III
- ✓Informed consent required
- ✕Age greater than 85 years
- ✕T1, N0 disease
- ✕T4b disease
- ✕BMI greater than 30
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Complete Mesocolic Excision With Central Vascular Ligation in Comparison With Conventional Surgery for the Right Colon Cancer: An Italian Randomized Trial
In Brief
A clinical study evaluating Conventional Right hemicolectomy (Non-CME) and Right hemicolectomy with CME+CVL for Colon Cancer. Currently recruiting, targeting 416 participants across 14 sites.
Detailed Summary
An Italian randomized controlled trial parallel-group in patients with a malignant tumor of the right or proximal transverse colon requiring right hemicolectomy.
Study Details
Timeline
Interventions
Transecting the Ileocolic Vein and Artery close to the Superior Mesenteric Vessels without clearing the superior mesenteric vein (SMV) from the adipose tissue. Transecting the Right Colic Vein and Artery and superior right colic vein (when present) peripherally. Transecting the Right branches of the Middle Colic Vein (MCV) and the Middle Colic Artery (MCA) peripherally, without clearing the main trunk of the MCV and the MCA. The Right Gastroepiploic Vein and artery are never transacted.
Separation of the visceral fascia from the parietal fascia by sharp dissection leaving intact mesocolon coverage. Transecting the supplying vessels at their origin from the main vessels, particularly: * The Ileocolic Vessels, The Right Colic Vessels,The superior right colic vein (when present), The Right branches of the Middle Colic Vein and of the Middle Colic Artery * The MCV and MCA at their origin in case of cancer of the hepatic flexure or of the proximal third of the transverse colon, as well as The Right Gastroepiploic Vessels at their origin from the gastrocolic trunk of Henle (GCTH) and the gastroduodenal artery. The SMV should be cleared from all adipose tissue all along its anterior surface until its intrapancreatic entrance.