CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 3,671 enrolled
Drug / intervention
Messaging informed by construal level theory +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04871776
NCT04871776N/ACompleted

Use of Construal Level Theory to Inform Messaging to Increase Vaccination Against COVID-19

Brigham and Women's Hospital·interventional·Posted May 4, 2021·Updated Jan 16, 2024

In Brief

A clinical study evaluating Messaging informed by construal level theory and Usual Care for Covid19 and Vaccine Refusal. Completed, enrolled 3,671 participants across 1 site.

Detailed Summary

This study aims to increase uptake of the COVID booster vaccine through messaging informed by Construal Level Theory. Patients in the Mass General Brigham (MGB) health system aged 18 and older who are eligible for the COVID booster vaccine, but who have not yet received a dose at the time of an upcoming primary care clinic visit, will be randomized to one of three messaging arms: 1) "why" messaging, 2) "how" messaging, or 3) standard of care ("usual care"). Messages will be sent via the electronic patient portal a few days in advance of their office visit. The primary outcome will be the rate of booster vaccination at the targeted visit. The secondary outcome will be the rate of receipt of a COVID booster vaccine within 6 weeks of the targeted visit. Subgroup analyses to assess for any association of patient characteristics with intervention responsiveness will be exploratory.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedMay 4, 2021
Enrollment StartFeb 18, 2022
Primary CompletionMay 27, 2022
Study CompletionAug 17, 2022
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 5.2 years ago

Interventions

Messaging informed by construal level theorybehavioral

Messages are informed by construal level theory, which suggests that emphasizing "why" elicits more abstract thinking, or high-level construals, and can induce an emotional mindset, which could challenge an individual's sense of identity, autonomy, or political preferences. Conversely, emphasizing "how" is more cognitive and evokes concrete thinking, or low-level construals, and encourages a planning or implementation mindset, which may be better for encouraging vaccine uptake.

Usual Carebehavioral

Usual messaging sent by Mass General Brigham