CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 714 enrolled
Drug / intervention
Surveyother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04872738
NCT04872738N/ACompleted

Patient Experiences With the COVID-19 Vaccination After Breast Cancer Treatment

Massachusetts General Hospital·observational·Posted May 4, 2021·Updated Jan 6, 2026

In Brief

An observational study evaluating Survey for Breast Cancer Related Lymphedema and Covid19. Completed, enrolled 714 participants across 1 site.

Detailed Summary

This study aims to elicit patient experiences, choices, and side effects associated with the COVID-19 vaccine after breast cancer surgery. Lymph node swelling is a known and common side effect of both the Moderna and Pfizer COVID-19 vaccines. This is the body's normal reaction to the vaccine. It is worrisome that lymph node swelling after the vaccine mimics that found in breast cancer which has spread to the lymph nodes. This side effect will cause worry and anxiety amongst patients as a result. For patients who have had lymph node removal (axillary lymph node dissection or sentinel lymph node biopsy) and are at risk of lymphedema, the investigators are concerned that the lymph node swelling may tax the lymphatic system and incite lymphedema in those at risk or worsen it in those with BCRL. Fear of lymphedema is high in this population and the investigators need to better understand what risk, if any, lymph node swelling after the COVID-19 vaccine imparts to BCRL risk.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedMay 4, 2021
Enrollment StartMay 7, 2021
Primary CompletionMar 17, 2023
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 5.2 years ago

Interventions

Surveyother

Patients in all groups will complete surveys about their experience with the vaccination and any side effects they may have experienced.