CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 106 enrolled
Drug / intervention
Engensis +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04873232
NCT04873232Phase 3Completed

A 6-Month Extension Study Following Protocol VMDN-003-2 - An Adaptive, Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess Engensis in Participants With Painful Diabetic Peripheral Neuropathy

Helixmith Co., Ltd.·interventional·Posted May 5, 2021·Updated Oct 9, 2025

In Brief

A Phase 3 clinical trial evaluating Engensis and Placebo for Diabetic Peripheral Neuropathy. Completed, enrolled 106 participants across 16 sites.

Detailed Summary

To evaluate the durability of efficacy and long-term safety of intramuscular administration of Engensis or Placebo that was administered in the double-blind, randomized, VMDN-003-2 Placebo-controlled Phase 3 Study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedMay 5, 2021
Enrollment StartMay 17, 2021
Primary CompletionSep 14, 2023
Study CompletionJul 23, 2024
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 5.2 years ago

Interventions

Engensisbiological

Injections with Engensis in study VMDN-003-2

Placeboother

Injections with Placebo in study VMDN-003-2