CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 231 enrolled
Drug / intervention
Efimosfermin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04880031
NCT04880031Phase 2Completed

A Phase 2a, Randomized, Blinded, Placebo-controlled Study of BOS-580 in Obese Subjects at Risk for, or With Biopsy-confirmed, Nonalcoholic Steatohepatitis (NASH) With a Single Arm Open-label Extension

Boston Pharmaceuticals·interventional·Posted May 10, 2021·Updated Oct 30, 2025

In Brief

A Phase 2 clinical trial evaluating Efimosfermin and Placebo for Nonalcoholic Steatohepatitis (NASH). Completed, enrolled 231 participants across 48 sites.

Detailed Summary

This is a randomized, blinded, placebo-controlled study of Efimosfermin in obese participants at risk for, or with biopsy-confirmed, nonalcoholic steatohepatitis (NASH), with a single arm open-label extension. It includes Parts A, B, C and D.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedMay 10, 2021
Enrollment StartSep 30, 2021
Primary CompletionOct 27, 2025
TodayJul 2, 2026
Enrollment to primary: 4.1 yearsPosted 5.1 years ago

Interventions

Efimosfermindrug

Efimosfermin will be administered by subcutaneous injection

Placebodrug

Placebo will be administered by subcutaneous injection