CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 132 enrolled
Drug / intervention
EsoCheck/EsoGuard (EC/EG) +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04880044
NCT04880044N/ACompleted
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Detection of Barrett s Esophagus in Patients Without Gastroesophageal Reflux Disease (GERD) Symptoms

Case Comprehensive Cancer Center·interventional·Posted May 10, 2021·Updated Mar 10, 2026

In Brief

A clinical study evaluating EsoCheck/EsoGuard (EC/EG) and Esophago-gastro-duodenoscopy (EGD) for Barrett's Esophagus. Completed, enrolled 132 participants across 1 site.

Detailed Summary

The purpose of this study is to develop a method to detect Barrett's esophagus (BE) in individuals with a new office-based diagnostic test.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBarrett's Esophagus
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedMay 10, 2021
Enrollment StartJan 5, 2022
Primary CompletionFeb 25, 2025
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 5.1 years ago

Interventions

EsoCheck/EsoGuard (EC/EG)other

EC is a swallowed capsule on a tethered catheter that obtains a touch sample of the distal esophagus. The obtained sample is placed in a buffer and sent to a diagnostics lab for testing of methylated markers from extracted DNA. EG is a methylated DNA test . A positive EG is associated with Barrett's esophagus at all its stages.

Esophago-gastro-duodenoscopy (EGD)other

SOC diagnostic endoscopic procedure that visualizes the upper part of the gastrointestinal tract down to the duodenum. Tissue samples collected.