CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
Transcranial Magnetic Stimulation +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04888494
NCT04888494N/ACompleted
CompareCT.gov

Enhancing Cortical-hippocampal Functional Connectivity as a Novel Means for Relieving Chronic Low Back Pain

Northwestern University·interventional·Posted May 17, 2021·Updated Jun 15, 2023

In Brief

A clinical study evaluating Transcranial Magnetic Stimulation and Sham rTMS for Chronic Pain and 2 related conditions. Completed, enrolled 16 participants across 1 site.

Detailed Summary

In this study the investigators aim to examine the effects of Transcranial Magnetic Stimulation (TMS) on hippocampal network connectivity and pain levels in individuals with chronic low back pain.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Pain, Back Pain, Pain
CountriesUnited States
CollaboratorsNational Institutes of Health (NIH), National Institute on Drug Abuse (NIDA)

Timeline

N/ACompletedFinished
20222023202420252026
First PostedMay 17, 2021
Enrollment StartJun 25, 2021
Primary CompletionJun 1, 2022
Study CompletionFeb 2, 2023
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 5.1 years ago

Interventions

Transcranial Magnetic Stimulationdevice

For the brain stimulation the investigators will use Repetitive Transcranial Magnetic stimulation (rTMS). Different stimulation conditions (hippocampal or sham) will be delivered in each round of stimulation (5 days). Repetitive TMS will be applied at 100% resting motor threshold intensity, 20 Hz pulse trains separated by 28-s inter-train intervals (\~20 minutes for the entire daily stimulation session). Stimulation parameters will be identical in both groups

Sham rTMSdevice

Sham rTMS