CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 231 enrolled
Drug / intervention
Mouthwash and nose rinse with the AgNPs solution +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04894409
NCT04894409N/ACompleted

Evaluation of Silver Nanoparticles as an Oropharyngeal Product (Mouthwash) and Nasal Hygiene, by Health Personnel Working at the Tijuana General Hospital Exposed to Patients Diagnosed With Atypical Pneumonia Caused by SARS-CoV-2

Cluster de Bioeconomia de Baja California, A.C·interventional·Posted May 20, 2021·Updated May 20, 2021

In Brief

A clinical study evaluating Mouthwash and nose rinse with the AgNPs solution and Mouthwashes and nose rinse in a conventional way for Coronavirus Disease 2019 (COVID-19). Completed, enrolled 231 participants across 1 site.

Detailed Summary

In this research, silver nanoparticles (AgNPs) were tested in vitro and shown to have an inhibitory effect on SARS-CoV-2 infection in cultured cells. Subsequently, the investigators assessed the effects of mouthwash and nose rinse with ARGOVIT® silver nanoparticles (AgNPs), in the prevention of SARS-CoV-2 contagion in health workers consider as high-risk group of acquiring the infection in the General Tijuana Hospital, Mexico, a hospital for the exclusive recruitment of patients diagnosed with COVID-19.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesMexico

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedMay 20, 2021
Enrollment StartApr 24, 2020
Primary CompletionJun 30, 2020
Study CompletionSep 29, 2020
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 5.1 years ago

Interventions

Mouthwash and nose rinse with the AgNPs solutiondevice

The "experimental" group was instructed to do mouthwash and nose rinse with the AgNPs solution for the prevention of SARS-CoV-2 infection in health workers

Mouthwashes and nose rinse in a conventional waydevice

The control group was instructed to do mouthwashes and nose rinse in a conventional way