CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 36 enrolled
Drug / intervention
Rosuvastatin (20mg) /Ezetimibe (10mg) in fixed dose +2 moredrug
Likely dose
Rosuvastatin (20mg) /Ezetimibe (10mg) in fixed dosefrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04895059
NCT04895059Phase 1Completed

Study of no Pharmacokinetic Interaction Between Rosuvastatin 20 mg and Ezetimibe 10 mg, Open Design, Randomized, Single Dose, 3x6, Crossove, Healthy Volunteers in Fasting, in Fixed Combination Against Individuals Components Managed

Laboratorios Silanes S.A. de C.V.·interventional·Posted May 20, 2021·Updated Aug 24, 2021

In Brief

A Phase 1 clinical trial evaluating Rosuvastatin (20mg) /Ezetimibe (10mg) in fixed dose, Rosuvastatin 20mg, and 1 other intervention for Healthy. Completed, enrolled 36 participants across 1 site.

Detailed Summary

Monocentric study of no pharmacokinetic interaction between rosuvastatin 20 mg and ezetimibe 10 mg. An open design, randomized, single dose with three periods, six sequences and crossed, in healthy volunteers with fasting conditions, managed in fixed dose combination (Sponsor Laboratorios Silanes S.A. de C.V.) versus individual components managed by separated (Crestor®, product of Astrazeneca, S.A. de C.V and Ezetrol®. product of Undra S.A. de C.V.)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesMexico
Collaborators--

Timeline

Phase 1CompletedFinished
201820192020202120222023202420252026
First PostedMay 20, 2021
Enrollment StartApr 30, 2017
Primary CompletionJan 15, 2018
Study CompletionJan 22, 2018
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 5.1 years ago

Interventions

Rosuvastatin (20mg) /Ezetimibe (10mg) in fixed dosedrug

Form: Tablets Dosage: 20 mg Adminstration way: Oral

Rosuvastatin 20mgdrug

Pharmaceutical Form: Tablets Dosage: 20 mg Adminstration way: Oral

Ezetimibe 10mgdrug

Pharmaceutical Form: Tablets Dosage: 10 mg Adminstration way: Oral