CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 73 enrolled
Drug / intervention
Oral Contraceptive Pill, norethindrn a-e estradiol-irondrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04899778
NCT04899778Phase 4Completed

Do Oral Contraceptives Protect Against Anterior Cruciate Ligament Injuries in Female Athletes

Cedars-Sinai Medical Center·interventional·Posted May 24, 2021·Updated May 1, 2025

In Brief

A Phase 4 clinical trial evaluating Oral Contraceptive Pill, norethindrn a-e estradiol-iron for Ligament Injury. Completed, enrolled 73 participants across 1 site.

Detailed Summary

The purpose of this research study is to examine the impact of one type of commonly used birth control pill on blood levels of relaxin and measure changes in knee movement to determine whether there are changes in joint instability (indicating the knee is less stable) that may predispose female athletes to injury. Women not on hormonal birth control will also be enrolled to analyze differences between athletes on and not on birth control and to evaluate typical relaxin levels and knee laxity when birth control pills are not used.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLigament Injury
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20222023202420252026
First PostedMay 24, 2021
Enrollment StartSep 29, 2021
Primary CompletionNov 20, 2023
Study CompletionJun 30, 2024
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 5.1 years ago

Interventions

Oral Contraceptive Pill, norethindrn a-e estradiol-irondrug

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