CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 66 enrolled
Drug / intervention
Betamethasone +1 moredrug
Likely dose
Betamethasone 6 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04900220
NCT04900220Phase 4Completed

Investigating Differences in Flare Reaction Incidence and Intensity Following Trigger Finger Injections Using Betamethasone and Methylprednisolone

West Virginia University·interventional·Posted May 25, 2021·Updated Jun 23, 2023

In Brief

A Phase 4 clinical trial evaluating Betamethasone and Methylprednisolone for Trigger Finger. Completed, enrolled 66 participants across 2 sites.

Detailed Summary

Two common corticosteroids used for trigger finger treatment are betamethasone and methylprednisolone. Both injections are effective in treating trigger finger and the decision of which to use in treatment is currently a matter of the current practice and physician preference. The goal through this randomized trial is to see whether there is a difference between these two corticosteroids in inducing flare reactions and if there are any differences in the peak level of pain and their duration. Findings indicating a statistically significant difference in the incidence and/or intensity of the flare reactions would be clinically significant and would be evidence supporting the switch of current practice to one corticosteroid over the other.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTrigger Finger
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20222023202420252026
First PostedMay 25, 2021
Enrollment StartSep 15, 2021
Primary CompletionDec 27, 2022
Study CompletionApr 10, 2023
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 5.1 years ago

Interventions

Betamethasonedrug

The volume of the doses of steroid to be given will be standardized to 1 injection of 1 cc of betamethasone (6 mg)

Methylprednisolonedrug

The volume of the doses of steroid to be given will be standardized to 1 injection of 1 cc of methylprednisolone (40 mg)