At a glance
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The Therapeutic Effects of Forced Aerobic Exercise in Multiple Sclerosis
In Brief
A clinical study evaluating Forced Aerobic Exercise (FE) and Voluntary Aerobic Exercise (VE) for Multiple Sclerosis. Completed, enrolled 22 participants across 2 sites.
Detailed Summary
This project will investigate the feasibility and initial efficacy of two aerobic exercise training approaches, forced and voluntary, to improve motor function in persons with multiple sclerosis (MS). We hypothesize that intensive aerobic exercise training elicits a neurorepairative and neurorestorative response on the central nervous system, which may improve motor function as it relates to gait and mobility. Should aerobic cycling, forced or voluntary, improve gait and functional mobility in persons with MS, it would serve as a new model to restoring function, rather than current models that focus on compensation.
Study Details
Timeline
Interventions
High-rate aerobic exercise on a semi-recumbent custom-designed stationary cycle ergometer
Voluntary-rate aerobic exercise on a semi-recumbent stationary cycle ergometer