CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 62 enrolled
Drug / intervention
Rectus sheath block with bupivacainedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04908449
NCT04908449Phase 1Completed
CompareCT.gov

A Comparison of the Analgesic Effects of Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery: a Prospective, Randomized Controlled Trial.

Medical College of Wisconsin·interventional·Posted Jun 1, 2021·Updated Nov 17, 2025

In Brief

A Phase 1 clinical trial evaluating Rectus sheath block with bupivacaine for Coronary Artery Disease and 2 related conditions. Completed, enrolled 62 participants across 1 site.

Detailed Summary

The purpose of this study is to determine if ultrasound-guided bilateral pectointercostal fascial plane blocks with bilateral rectus sheath blocks block decrease pain scores, decrease opioid consumption, improve respiratory function, and improve quality of recovery in patients recovering from elective cardiac surgery involving primary median sternotomy and mediastinal chest tubes in comparison to pectointercostal fascial plane blocks alone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCoronary Artery Disease, Postoperative Pain, Respiratory Failure
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedJun 1, 2021
Enrollment StartJun 19, 2023
Primary CompletionNov 8, 2024
Study CompletionNov 14, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 5.1 years ago

Interventions

Rectus sheath block with bupivacainedrug

Rectus sheath block with local anesthetic versus sham block with saline