CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,609 enrolled
Drug / intervention
Ad26.COV2.Sbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04908722
NCT04908722Phase 3Completed

A Randomized, Double-blind, Phase 3 Study to Evaluate 6 Dose Levels of Ad26.COV2.S Administered As a Two-Dose Schedule in Healthy Adults

Janssen Vaccines & Prevention B.V.·interventional·Posted Jun 1, 2021·Updated Feb 4, 2025

In Brief

A Phase 3 clinical trial evaluating Ad26.COV2.S for COVID-19 Prevention. Completed, enrolled 1,609 participants across 43 sites in 5 countries.

Detailed Summary

The purpose of this study is to demonstrate non-inferiority (NI) in terms of humoral immune responses after 6 dose levels of Ad26.COV2.S.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBrazil, Germany, Poland, South Africa, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedJun 1, 2021
Enrollment StartJun 18, 2021
Primary CompletionJul 10, 2023
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 5.1 years ago

Interventions

Ad26.COV2.Sbiological

Participants will receive intramuscular (IM) injections of Ad26.COV2.S.