CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 226 enrolled
Drug / intervention
Nebivolol Ophthalmic Suspension 1 Percent +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04910100
NCT04910100Phase 2Completed

Randomized, Multicenter, Observer-Masked Study to Compare Safety/Efficacy of Nebivolol Suspension 0.5% or 1.0%, or Timolol Suspension 0.5% to Timolol Solution 0.5% in Participants With Primary Open Angle Glaucoma or Ocular Hypertension

Betaliq, Inc.·interventional·Posted Jun 2, 2021·Updated Apr 17, 2024

In Brief

A Phase 2 clinical trial evaluating Nebivolol Ophthalmic Suspension 1 Percent, Nebivolol Ophthalmic Suspension 0.5 Percent, and 2 other interventions for Open-Angle Glaucoma and Ocular Hypertension. Completed, enrolled 226 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate the safety (in the eye and throughout the body) and effectiveness of nebivolol (0.5 and 1 percent) and timolol (0.5 percent) eye drop suspensions. These eye drops will be compared to timolol 0.5 percent eye drop solution in participants with open angle glaucoma (the most common type of glaucoma) or high eye pressure (ocular hypertension).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedJun 2, 2021
Enrollment StartApr 15, 2021
Primary CompletionMar 31, 2022
Study CompletionApr 29, 2022
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 5.1 years ago

Interventions

Nebivolol Ophthalmic Suspension 1 Percentdrug

1 drop instilled into each eye twice daily

Nebivolol Ophthalmic Suspension 0.5 Percentdrug

1 drop instilled into each eye twice daily

Timolol Ophthalmic Suspension 0.5 Percentdrug

1 drop instilled into each eye twice daily

Timolol Ophthalmic Solution 0.5 Percentdrug

1 drop instilled into each eye twice daily