CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 3,635 enrolled
Drug / intervention
Clinical Decision Support (CDS) alertsother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04918355
NCT04918355N/ACompleted

A Health System Wide Evaluation of Mandated Use and Clinical Decision Support Tools to Improve PDMP Utilization and Patient Outcomes

University of Colorado, Denver·observational·Posted Jun 8, 2021·Updated Sep 16, 2025

In Brief

An observational study evaluating Clinical Decision Support (CDS) alerts for Medication Abuse. Completed, enrolled 3,635 participants across 1 site.

Detailed Summary

This is a study comparing three clinical decision support (CDS) tools to enhance care by easing health care provider review of the Colorado prescription drug monitoring program (PDMP) prior to prescribing opioids (pain medications often called narcotics) or benzodiazepines (sedatives or muscle relaxants). The tools screen information from the PDMP (a statewide database of filled controlled medication) and a patient's medical record to identify high-risk factors for overdose. The tools only appear when relevant, are purely informational to facilitate an evidence-based practice (PDMP review) and do not dictate care or suggest changes in treatment. The study will track how each of the tools are used and if providers use the PDMP. Secondary outcomes include if a controlled medication prescription was written and future opioid use by patients.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJun 8, 2021
Enrollment StartFeb 16, 2021
Primary CompletionMay 30, 2023
Study CompletionNov 30, 2023
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 5.1 years ago

Interventions

Clinical Decision Support (CDS) alertsother

CDS alerts are pop-up boxes integrated into the EHR. Each alert provides patient specific information, a link to the PDMP, instructions on how to dismiss the alert, a link to study-specific educational website, and a comment field.