CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 163 enrolled / 163 target
Drug / intervention
TAR-200 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04919512
NCT04919512Phase 2CompletedMonitor (3.4/mo)Completion was 16mo ago

A Phase 2, Open-Label, Multi-Center, Randomized Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder Who Are Scheduled for Radical Cystectomy and Are Ineligible for or Refusing Platinum-Based Neoadjuvant Chemotherapy

Janssen Research & Development, LLC·interventional·Posted Jun 9, 2021·Updated Jun 23, 2026

In Brief

A Phase 2 clinical trial evaluating TAR-200 and Cetrelimab for Urinary Bladder Neoplasms. Completed, enrolled 163 participants across 109 sites in 10 countries.

Signals

Enrolling slower than its timeline implies

Detailed Summary

The purpose of this study is to evaluate the anti-tumor effects of TAR-200 in combination with intravenous (IV) cetrelimab and IV cetrelimab alone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, France, Germany, Israel, Italy, Netherlands, South Korea, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedJun 9, 2021
Enrollment StartJul 7, 2022
Primary CompletionFeb 4, 2025
Study CompletionMar 31, 2026
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 5.1 years ago

Arms & Interventions

Cohort 1: TAR-200 + Cetrelimabexperimental

Participants will receive TAR-200 in combination with cetrelimab.

Drug: TAR-200Biological: Cetrelimab
Cohort 2: Cetrelimabexperimental

Participants will receive cetrelimab.

Biological: Cetrelimab

Interventions

TAR-200drug

TAR-200 will be administered.

Cetrelimabbiological

Cetrelimab will be administered.