CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 100 enrolled
Drug / intervention
Bupivacaine Injection +2 moredrug
Likely dose
Bupivacaine Injection 10mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04928339
NCT04928339Phase 4Completed
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Pecto-Intercostal Fascial Plane Block for Enhanced Recovery After Cardiac Surgery

University of Wisconsin, Madison·interventional·Posted Jun 16, 2021·Updated Nov 19, 2024

In Brief

A Phase 4 clinical trial evaluating Bupivacaine Injection, Liposomal bupivacaine, and 1 other intervention for Cardiac Surgery and Opioid Use, Unspecified. Completed, enrolled 100 participants across 1 site.

Detailed Summary

This study is being done to see if bilateral pecto-intercostal fascial plane blocks (PIFB) with a mixture of liposomal and standard bupivacaine decrease pain and opioid requirements in patients undergoing cardiac surgery via median sternotomy compared to controls (sham blocks with saline). 100 participants will be recruited and can expect to be on study for 100 days.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCardiac Surgery, Opioid Use, Unspecified
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20222023202420252026
First PostedJun 16, 2021
Enrollment StartMar 28, 2022
Primary CompletionSep 3, 2023
Study CompletionNov 30, 2023
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 5.0 years ago

Interventions

Bupivacaine Injectiondrug

10mL of 0.25% bupivacaine

Liposomal bupivacainedrug

15mL of 133mg liposomal bupivacaine

Salineother

25mL saline control