CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 126 enrolled
Drug / intervention
Magnesium Sulfate 500 mg/ml+ ventolin +1 moredrug
Likely dose
Magnesium Sulfate 500 mg/ml+ ventolinfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04929626
NCT04929626Phase 1Completed
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Comparison of Doses of Nebulized Magnesium Sulphate as an Adjuvant Treatment With Salbutamol in Children With Status Asthmaticus

Ziauddin University·interventional·Posted Jun 18, 2021·Updated Apr 5, 2023

In Brief

A Phase 1 clinical trial evaluating Magnesium Sulfate 500 mg/ml+ ventolin and Ventolin for Status Asthmaticus. Completed, enrolled 126 participants across 1 site.

Detailed Summary

In this study investigators will use magnesium sulphate in the nebulized form in children between 2 and 12 years of age as an acute reliever for acute severe asthma. Aim of this study is to determine that whether adding low (250mg), intermediate (500mg), and high doses (750mg) of magnesium sulphate in the 1st hour of treatment has any difference in the improvement of clinical condition of the patient and length of hospital stay. There will be total 108 patients having 2 groups. 1st group will receive only Ventolin while 2nd group will be given Ventolin and Magnesium sulphate.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStatus Asthmaticus
CountriesPakistan
Collaborators--

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedJun 18, 2021
Enrollment StartJan 1, 2022
Primary CompletionNov 12, 2022
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 5.0 years ago

Interventions

Magnesium Sulfate 500 mg/ml+ ventolindrug

3 doses of magnesium sulphate i.e; 250mg(0.5ml), 500mg(1ml), 750mg(1.5ml) will be used in nebulized form

Ventolindrug

it will be given to control group in nebulized form after every 20 min in 1st hour