CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 211 enrolled
Drug / intervention
vafidemstat +1 moredrug
Likely dose
vafidemstat 1.2mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04932291
NCT04932291Phase 2Completed

"A Double-blind, Randomized, Placebo-controlled, Adaptive 14-week Phase IIb Trial to Evaluate the Efficacy and Safety of Vafidemstat in an Adult Borderline Personality Disorder (BPD) Population (PORTICO)"

Oryzon Genomics S.A.·interventional·Posted Jun 21, 2021·Updated May 5, 2026

In Brief

A Phase 2 clinical trial evaluating vafidemstat and Placebo for Borderline Personality Disorder. Completed, enrolled 211 participants across 21 sites in 5 countries.

Detailed Summary

PORTICO is a Phase IIb study to evaluate the efficacy and safety of vafidemstat in an adult borderline personality disorder (BPD) population.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBulgaria, Germany, Serbia, Spain, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedJun 21, 2021
Enrollment StartMar 26, 2021
Primary CompletionOct 30, 2023
Study CompletionNov 13, 2023
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 5.0 years ago

Interventions

vafidemstatdrug

1.2mg capsule

Placebodrug

placebo capsule